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Muromonab CD3

《英文msh詞典》Muromonab CD3
[入口詞] Muromonab CD3
[主題詞] Muromonab-CD3
[藥動學(xué)] Immunosuppressive Agents
[英文釋義] Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti). This biochemically purified IMMUNOGLOBULIN G is obtained through the fusion of mouse myeloma cells to lymphocytes from immunized animals to produce hybridomas that secrete specific antibodies to the T3 (CD3) antigens of human T-lymphocytes. It is often used as an immunosuppressive agent in transplantation.